Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
نویسندگان
چکیده
منابع مشابه
Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
Unexpected degradation of the P-C-P bridge from novel bisphosphonate derivative 1a and known etidronate trimethyl ester (1b) has been observed under mild reaction conditions. A proposed reaction mechanism for the unexpected degradation of 1a and 1b is also reported.
متن کاملOxidation of a P-C Bond under Mild Conditions.
The reactivity of phosphenium dication [(Ph3P)2C-P-NiPr2](2+), 1(2+), towards pyridine N-oxide (O-py) has been investigated. The resulting oxophosphonium dication [(Ph3P)2C(NiPr2)P(O)(O-py)](2+), 2(2+), was surprisingly stabilized by a less nucleophilic O-py ligand instead of pyridine (py). This compound was then identified as an analogue of the elusive Criegee intermediate as it underwent oxyg...
متن کاملOn the Reaction of Carbonyl Diphosphonic Acid with Hydroxylamine and O-alkylhydroxylamines: Unexpected Degradation of P-C-P Bridge.
Derivatives of methylenediphosphonic acid possess wide spectra of biological activities and are used in enzymology as research tools as well as in practical medicine. Carbonyl diphosphonic acid is a promising starting building block for synthesis of functionally substituted methylenediphosphonates. Investigation of the interaction of carbonyl diphosphonic acid with hydroxylamine clearly demonst...
متن کاملMethyl orange degradation over nano-LaMnO3 as a green catalyst under the mild conditions
This study was conducted to investigate the use of cubic LaMnO3 nano-perovskite as a green catalyst for the degradation of an aqueous solution of methyl orange under different conditions. Nanoscale cubic lanthanum manganite with the particle size of ~20 nm was successfully synthesized via citrate sol-gel method. The sample was characterized using the FT-IR and UV-Vis spectroscopy, XRD, SEM, and...
متن کاملCompetition graphs of semiorders and the conditions C(p) and C*(p)
Given a digraph D, its competition graph has the same vertex set and an edge between two vertices x and y if there is a vertex u so that (x, u) and (y, u) are arcs of D. Motivated by a problem of communications, we study the competition graphs of the special digraphs known as semiorders. This leads us to define a conditions on digraphs called C(p) and C(p) and to study the graphs arising as com...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Beilstein Journal of Organic Chemistry
سال: 2008
ISSN: 1860-5397
DOI: 10.1186/1860-5397-4-7